JAK2 monoclonal antibody, clone 691R5
产品名称： JAK2 monoclonal antibody, clone 691R5
英文名称： JAK2 monoclonal antibody, clone 691R5
产品编号： MAB1906
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against full length recombinant JAK2.
- Immunogen:
- Recombinant protein corresponding to full length human JAK2.
- Host:
- Mouse
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Isotype:
- IgG2b
- Storage Buffer:
- In PBS, pH 7.2 (1.0% BSA, 0.08% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- Western Blot (1-5 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Distinct mechanisms of receptor and nonreceptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: role of metalloprotease and protein kinase C-delta.
Frank GD, Mifune M, Inagami T, Ohba M, Sasaki T, Higashiyama S, Dempsey PJ, Eguchi S.Mol Cell Biol. 2003 Mar;23(5):1581-9.
- 2.
- Protein tyrosine phosphatase 1B negatively regulates leptin signaling in a hypothalamic cell line.
Kaszubska W, Falls HD, Schaefer VG, Haasch D, Frost L, Hessler P, Kroeger PE, White DW, Jirousek MR, Trevillyan JM.Mol Cell Endocrinol. 2002 Sep 30;195(1-2):109-18.
- 3.
- Thrombopoietin regulates Bcl-xL gene expression through Stat5 and phosphatidylinositol 3-kinase activation pathways.
Kirito K, Watanabe T, Sawada K, Endo H, Ozawa K, Komatsu N.J Biol Chem. 2002 Mar 8;277(10):8329-37. Epub 2001 Dec 27.
- Entrez GeneID:
- 3717
- Protein Accession#:
- O60674
- Gene Name:
- JAK2
- Gene Alias:
- JTK10
- Gene Description:
- Janus kinase 2 (a protein tyrosine kinase)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq
- Other Designations:
- Janus kinase 2,OTTHUMP00000021024,OTTHUMP00000043260,tyrosine-protein kinase JAK2
- Related Disease
- Acute Disease
- Anemia, Iron-Deficiency
- Anemia, Refractory
- Arterial Occlusive Diseases
- Asthma
- Asthma
- Blast Crisis
- Breast cancer
- Breast Neoplasms
- Bronchiolitis, Viral
- Budd-Chiari Syndrome
- Carcinoma
- Carcinoma, Ductal, Breast
- Carcinoma, Non-Small-Cell Lung
- Cardiovascular Diseases
- Cell Transformation, Neoplastic
- Chromosome Aberrations
- Chronic Disease
- Colitis, Ulcerative