FITC标记的ras癌基因家族Rab2抗体
产品名称： FITC标记的ras癌基因家族Rab2抗体
英文名称： Anti-RAB2/FITC
产品编号： HZ-6174R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-RAB2/FITC Conjugated antibody
FITC标记的ras癌基因家族Rab2抗体
| 英文名称 | Anti-RAB2/FITC |
| 中文名称 | FITC标记的ras癌基因家族Rab2抗体 |
| 别 名 | GTP binding protein; RAB2; RAB2 member RAS oncogene family; RAB2A; RAB2A, member RAS oncogene family; RAB2A_HUMAN; Ras related protein Rab 2A; RAS-associated protein RAB2; Ras-related protein Rab-2A; RP23-183L6.1 |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 信号转导 转录调节因子 G蛋白偶联受体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 23kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RAB2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Function: Required for protein transport from the endoplasmic reticulum to the Golgi complex. Subunit: Interacts with PRKCI. Subcellular Location: Endoplasmic reticulum-Golgi intermediate compartment membrane; Lipid-anchor. Melanosome. Endoplasmic reticulum membrane; Lipid-anchor (Potential). Golgi apparatus membrane; Lipid-anchor (Potential). Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Similarity: Belongs to the small GTPase superfamily. Rab family. Database links: UniProtKB/Swiss-Prot: P61019.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
由该基因编码的蛋白质属于Rab家族，其成员是小分子量鸟苷三磷酸酶（GTPASE），其包含与GTP结合和水解有关的高度保守结构域。Rabs是膜结合蛋白，参与囊泡融合和贩运。这种蛋白质是高尔基体前体的驻留物，需要从内质网（ER）转运到高尔基复合体。另一种编码不同的异构体的剪接转录变体已被发现用于该基因。