C20orf186,20号染色体开放阅读框186抗体

产品编号HZ-15102R
英文名称C20orf186
中文名称20号染色体开放阅读框186抗体
别 名C20orf186; dJ726C3.5; Ligand-binding protein RY2G5; Long palate, lung and nasal epithelium carcinoma-associated protein 4; LPLC4_HUMAN; Lplunc4.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Horse,
C20orf186,20号染色体开放阅读框186抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量63kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human C20orf186
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
C20orf186,20号染色体开放阅读框186抗体PubMedPubMed
产品介绍background:
LPLUNC4 is a 614 amino acid secreted protein that belongs to the BPI/LBP/PLUNC superfamily. Expressed in nasal tissue, LPLUNC4 has the capacity to recognize and bind specific classes of odorants serving as a primary defense mechanism in the mucosa. LPLUNC4 is encoded by a gene which maps to a BPI/LBP/PLUNC gene cluster on human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome

Function:
May have the capacity to recognize and bind specific classes of odorants. May act as a carrier molecule, transporting odorants across the mucus layer to access receptor sites. May serve as a primary defense mechanism by recognizing and removing potentially harmful odorants or pathogenic microorganisms from the mucosa or clearing excess odorant from mucus to enable new odorant stimuli to be received (By similarity).

Subcellular Location:
Secreted (By similarity). Cytoplasm.

Tissue Specificity:
Expressed in nasal tissue.

Similarity:
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

C20orf186,20号染色体开放阅读框186抗体Database links:
Entrez Gene: 149954 Human
Entrez Gene: 499925 Rat
SwissProt: P59827 Human
SwissProt: Q05704 Rat
Unigene: 38961 Human
Unigene: 117356 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.