Cecropin,抗菌肽/天蚕素抗体

产品编号HZ-2080R
英文名称Cecropin
中文名称抗菌肽/天蚕素抗体
说 明 书0.1ml 0.2ml
产品类型植物抗体
研究领域细菌及病毒 植物
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Hyalophora cecropia
Cecropin,抗菌肽/天蚕素抗体产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量4kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide from Hyalophora cecropia Cecropin
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Cecropin,抗菌肽/天蚕素抗体PubMedPubMed
产品介绍background:
Cecropins are antimicrobial peptides.They were first isolated from the hemolymph of Hyalophora cecropia, from whence the term cecropin was derived. Cecropins lyse bacterial cell membranes; they also inhibit proline uptake and cause leaky membranes. Cecropins constitute a main part of the cell-free immunity of insects. Cecropins are small proteins of about 31 - 37 amino acid residues active against both Gram-positive and Gram-negative bacteria. Cecropins isolated from insects other than Hyalophora cecropia (Cecropia moth) have been given various names; bactericidin, lepidopteran, sarcotoxin, etc. All of these peptides are structurally related. Cecropin P1, an intestinal antibacterial peptide from Sus scrofa (Pig), also belongs to this family. Cecropin family also consists Cecropin A and Cecropin B.

Function:
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.

Subcellular Location:
Secreted.

Post-translational modifications:
A protein with the same sequence as cecropin A, but lacking the carboxyl blocking group, has been isolated and called cecropin C (PubMed:7140755).

Similarity:
Belongs to the cecropin family.

Cecropin,抗菌肽/天蚕素抗体Database links:
GenBank: AAP93872

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Cecropin抗菌肽又称天蚕素，具有抗菌、抗病毒、抗肿瘤等活性，因其水溶性好，耐高温，是一种比较理想的抗生素代用品；尤其是其主要抑菌机制,可破坏细胞膜的稳定性，不易产生耐药性。 抗菌肽一般是小肽，可以被动物完全消化，不存在残留性的问题，所以，抗菌肽无论是作为饲料添加剂，兽药还是人药，都有理论上的研究价值和生产中的实际意义。