ITGA1 polyclonal antibody
产品名称： ITGA1 polyclonal antibody
英文名称： ITGA1 polyclonal antibody
产品编号： PAB12281
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ITGA1.
- Immunogen:
- A synthetic peptide corresponding to amino acids at C-terminus of human ITGA1.
- Sequence:
- KIGFFKRPLKKKMEK
- Host:
- Rabbit
- Theoretical MW (kDa):
- 130.8
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- Identical to the related mouse sequence.
- Form:
- Liquid
- Purification:
- Affinity purification
- Concentration:
- 200 ug/mL
- Storage Buffer:
- In 1.2% sodium acetate (5% BSA, 0.01% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Polymorphisms and haplotypes of integrinalpha1 (ITGA1) are associated with bone mineral density and fracture risk in postmenopausal Koreans.
Lee HJ, Kim SY, Koh JM, Bok J, Kim KJ, Kim KS, Park MH, Shin HD, Park BL, Kim TH, Hong JM, Park EK, Kim DJ, Oh B, Kimm K, Kim GS, Lee JY.Bone. 2007 Dec;41(6):979-86. Epub 2007 Sep 5.
- 2.
- Diminished callus size and cartilage synthesis in alpha 1 beta 1 integrin-deficient mice during bone fracture healing.
Ekholm E, Hankenson KD, Uusitalo H, Hiltunen A, Gardner H, Heino J, Penttinen R.Am J Pathol. 2002 May;160(5):1779-85.
- 3.
- Genetic mapping of the integrin alpha 1 gene (Vla1) to mouse chromosome 13.
Douville P, Seldin MF, Carbonetto S.Genomics. 1992 Oct;14(2):503-5.
- Entrez GeneID:
- 3672
- GeneBank Accession#:
- BC137121
- Protein Accession#:
- AAI37122
- Gene Name:
- ITGA1
- Gene Alias:
- CD49a,VLA1
- Gene Description:
- integrin, alpha 1
- Omim ID:
- 192968
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq
- Other Designations:
- laminin and collagen receptor,very late activation protein 1