SORCS3,液泡蛋白分选受体SORCS3抗体

产品编号HZ-11503R
英文名称SORCS3
中文名称液泡蛋白分选受体SORCS3抗体
别 名6330404A12Rik; KIAA1059; RP11 107L7.1; SORC3_HUMAN; SORCS 3; SORCS; SORCS3; Sortilin related VPS10 domain containing receptor 3; VPS10 domain containing receptor SorCS3; VPS10 domain receptor protein SORCS 3; VPS10 domain-containing receptor SorCS3.
说 明 书0.1ml 0.2ml
研究领域细胞生物 神经生物学 生长因子和激素
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,
SORCS3,液泡蛋白分选受体SORCS3抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量132kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human SORCS3
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
SORCS3,液泡蛋白分选受体SORCS3抗体PubMedPubMed
产品介绍background:
This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Highly expressed in brain.

Similarity:
Belongs to the VPS10-related sortilin family. SORCS subfamily.
Contains 6 BNR repeats.
Contains 1 PKD domain.

Database links:
UniProtKB/Swiss-Prot: Q9UPU3.2

SORCS3,液泡蛋白分选受体SORCS3抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.