分子量:10.4 kDa

纯度:>95% as determined by SDS-PAGE.

内毒素:Less than 1.0 EU per μg of the Human S100P, Tag Free by the LAL method.

Buffer:50 mM Tris,150 mM Nacl,pH8.0

生物活性:

产品特性:Human S100P, Tag Free contains no "tag", and has a calculated MW of 10.4 kDa. The predicted N-terminus is Met. The reducing (R) protein migrates as 10.4 kDa in SDS-PAGE .

产品背景:S100 calcium-binding protein P (S100P),a member of the S-100 family, is also known as protein S100-P, migration-inducing gene 9 protein (MIG9) and protein S100-E,which contains two EF-hand domains. As for subunit structure,S100P is homodimer and heterodimer with S100A1. S100P may function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, S100P functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. Furthermore,S100P may stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).