Anti-C-flanking peptide of NPY/FITC Conjugated抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-C-flanking peptide of NPY/FITC Conjugated抗体

Anti-C-flanking peptide of NPY/FITC Conjugated抗体

商家询价

产品名称: Anti-C-flanking peptide of NPY/FITC Conjugated抗体

英文名称: Anti-C-flanking peptide of NPY/FITC

产品编号: YB--20693R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-C-flanking peptide of NPY/FITC Conjugated抗体

产品编号 YB-20693R-FITC
英文名称 Anti-C-flanking peptide of NPY/FITC
中文名称 FITC标记的C-侧翼肽NPY抗体
别    名 Neuropeptide tyrosine; Neuropeptide Y precursor; NPY; PYY 4; PYY4; Y Neuropeptide; NPY_HUMAN; Pro-neuropeptide Y; CPON.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 神经生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 3.3/8kDa
性    状 Lyophilized or Liquid
浓    度 2mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human C-flanking peptide of NPY
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]
Neuropeptide Y (NPY) is a 36 amino acid peptide neurotransmitter found in the brain and autonomic nervous system. NPY has been associated with a number of physiologic processes in the brain, including the regulation of energy balance, memory and learning, and epilepsy.The main effect is increased food intake and decreased physical activity. NPY is secreted by the hypothalamus, and in addition to increasing food intake, it increases the proportion of energy stored as fat and blocks nociceptive signals to the brain NPY also augments the vasoconstrictor effects of noradrenergic neurons.

Function:
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.

Subcellular Location:
Secreted.

Tissue Specificity:
One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla.

Post-translational modifications:
The neuropeptide Y form is cleaved at Pro-30 by the prolyl endopeptidase FAP (seprase) activity (in vitro).

Similarity:
Belongs to the NPY family.

Database links:

Entrez Gene: 4852 Human

Entrez Gene: 109648 Mouse

Entrez Gene: 24604 Rat

Omim: 162640 Human

SwissProt: P01303 Human

SwissProt: P57774 Mouse

SwissProt: P68006 Rabbit

SwissProt: P07808 Rat

Unigene: 1832 Human

Unigene: 154796 Mouse

Unigene: 9714 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications