FITC标记的神经元X连锁蛋白/儿童自闭症相关蛋白抗体
产品名称： FITC标记的神经元X连锁蛋白/儿童自闭症相关蛋白抗体
英文名称： Anti-NLGN4X/FITC
产品编号： HZ-11099R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-NLGN4X/FITC Conjugated antibody
FITC标记的神经元X连锁蛋白/儿童自闭症相关蛋白抗体
| 产品编号 | bs-11099R-FITC |
| 英文名称 | Anti-NLGN4X/FITC |
| 中文名称 | FITC标记的神经元X连锁蛋白/儿童自闭症相关蛋白抗体 |
| 别 名 | X-linked; HNLX; KIAA1260; Neuroligin X; Neuroligin-4; NLGN4; NLGN 4; NLGN4X; Neuroligin 4 X linked; Neuroligin 4; Neuroligin X; NLGN; NLGN-4; NLGN4X; NLGN4Y; NLGNX_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 发育生物学 神经生物学 细胞粘附分子 细胞膜蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Horse, Zebrafish, Chimpanzee, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 92kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NLGN4X |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large (Drosophila) homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]. Function: Putative neuronal cell surface protein involved in cell-cell-interactions. Subunit: Belongs to the type-B carboxylesterase/lipase family. Subcellular Location: Membrane. Tissue Specificity: Expressed at highest levels in heart. Expressed at lower levels in liver, skeletal muscle and pancreas and at very low levels in brain. DISEASE: Defects in NLGN4X may be the cause of susceptibility to autism X-linked type 2 (AUTSX2). AUTSX2 is a pervasive developmental disorder (PDD), prototypically characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age. Defects in NLGN4X may be the cause of susceptibility to X-linked Asperger syndrome 2 (ASPGX2). ASPGX2 is considered to be a form of childhood autism. Similarity: Belongs to the type-B carboxylesterase/lipase family. Database links: Entrez Gene: 57502 Human Omim: 300427 Human SwissProt: Q8N0W4 Human Unigene: 21107 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码神经元细胞表面蛋白家族的成员。该家族成员可作为β-奈鲁星的剪接位点特异性配体，并可能参与中枢神经系统突触的形成和重塑。编码的蛋白质与椎间盘，大（果蝇）同源物4（DLG4）相互作用。该基因的突变与孤独症和阿斯伯格综合症有关。两个编码相同蛋白的转录变体已被鉴定为该基因。[ RefSeq，JUL 2008 ]提供。