ARP5/ACTR5抗体
Applications
| In-house applications |
ELISA, WB, IF, IP Application not tested? Please see our Guarantee. |
| Published applications |
IF, WB |
Publications |
1 citations –view here |
| Species specificity |
Human,Mouse,Rat; other species not tested. |
| Published Species |
Rat |
|
Images
Prev1Next
 mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 21505-1-AP(ACTR5 antibody) at dilution of 1:500 IP Result of anti-ACTR5 (IP:21505-1-AP, 4ug; Detection:21505-1-AP 1:500) with HEK-293 cells lysate 1120ug. Immunofluorescent analysis of A549 cells using 21505-1-AP( ACTR5 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
|
| Positive WB detected in |
Mouse cerebellum tissue, HEK-293 cells, human skeletal muscle tissue, mouse heart tissue, mouse ovary tissue |
| Positive IP detected in |
HEK-293 cells |
| Positive IF detected in |
A549 cells, HepG2 cells |
| Recommended dilution |
WB : 1:1000-1:10000
IP : 1:200-1:2000
IF : 1:10-1:100 |
ARP5/ACTR5抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
| Source |
Rabbit |
Purification method |
Antigen affinity purification |
| Isotype |
IgG |
Storage |
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information ARP5/ACTR5抗体
| Immunogen |
Arp5/ACTR5 fusion protein ag15976 |
Full name |
ARP5 actin-related protein 5 homolog (yeast) |
Calculated molecular
weight |
607aa,68 kDa |
Observed molecular
weight |
68 kDa |
GenBank accession
number |
BC038402 |
Gene ID (NCBI) |
79913 |
| Gene symbol |
ACTR5 |
Synonyms |
Actin related protein 5, ACTR5, Arp5, hARP5, Sarcoma antigen NY SAR 16 |
Background
|
Arp5 is a member of nuclear actin-related proteins (ARPs) that function as components of the chromatin- remodeling complex. Recently study reported that Arp5 regulates smooth muscle cell differentiation through interaction with myocardin (Myocd). Arp5 has been identified as negative regulator of Myocd, suppressing Myocd activity in the nucleus through tightly binding with Myocd RPEL motifs. Alternative splicing results in two variants of Arp5: a broadly expressed arp5-common, and a smooth muscle restricted arp5-sm. Expression of Arp5-sm protein is strongly suppressed in well-differentiated smooth muscle cells by partial messenger RNA decay and translational suppression. (24567363) ARP5/ACTR5抗体
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