ITGAV monoclonal antibody, clone 13C2
产品名称： ITGAV monoclonal antibody, clone 13C2
英文名称： ITGAV monoclonal antibody, clone 13C2
产品编号： MAB6229
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native ITGAV.
- Immunogen:
- Native purified from human osteoclastoma tissue.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- human CD51.
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In 100 mM BBS, pH 8.2
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- Flow Cytometry (1 ug/106 cells)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Platelet integrins.
Ginsberg MH, Xiaoping D, O'Toole TE, Loftus JC, Plow EF.Thromb Haemost. 1993 Jul 1;70(1):87-93.
- 2.
- Platelet membrane glycoproteins: functions in cellular interactions.
Kieffer N, Phillips DR.Annu Rev Cell Biol. 1990;6:329-57.
- Application Image
- Immunohistochemistry (Frozen sections)
- Flow Cytometry
- Entrez GeneID:
- 3685
- Gene Name:
- ITGAV
- Gene Alias:
- CD51,DKFZp686A08142,MSK8,VNRA
- Gene Description:
- integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
- Omim ID:
- 193210
- Gene Ontology:
- Hyperlink
- Gene Summary:
- ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq
- Other Designations:
- Integrin, alpha-V (vitronectin receptor, alpha polypeptide),antigen identified by monoclonal antibody L230,integrin alpha-V
- Related Disease
- Anemia, Sickle Cell
- Anemia, sickle cell
- Arthritis, Rheumatoid
- Breast cancer
- Breast Neoplasms
- Carcinoma, Hepatocellular
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Hepatitis B, Chronic
- Ovarian Neoplasms
- Priapism
- Thalassemia
- Thalassemia
- Tobacco Use Disorder