重组人白细胞介素-1α（人白细胞介素-1α）
产品名称： 重组人白细胞介素-1α（人白细胞介素-1α）
英文名称： Recombinant Human Interleukin-1 alpha (Human IL-1α)
产品编号： 90100ES10
产品价格： 535.00
产品产地： 翌圣生物
品牌商标： Yeasen
更新时间： 2024-04-26T15:09:37
使用范围： null
| 规格 | 价格 |
| 2 μg | 535.0 |
| 10 μg | 1855.0 |
| 50 μg | 3855.0 |
| 100 μg | 6175.0 |
| 500 μg | 16773.0 |
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Human Interleukin-15 (IL-15) is a widely expressed 14 kDa cytokine that is plays an important role in many immunological diseases. It shares approximately 97% and 73% sequence identity with simian and murine IL-15, respectively. Both human and simian IL-15 are active on murine cells. IL-15 is secreted by mononuclear phagocytes (and some other cells), especially macrophages following infection by virus. IL-15 and IL-2 have similar biologic properties in vitro, consistent with their shared receptor (R) signaling components (IL-2/15Rβγc). A role for IL-15 during autoimmune processes such as rheumatoid arthritis and malignancies such as adult T-cell leukemia suggest that dysregulation of IL-15 may result in deleterious effects for the host.
Product Properties
|
Synonyms |
Interleukin-15, IL-15, MGC9721 |
|
Accession |
|
|
GeneID |
|
|
Source |
E.coli-derived human IL-15 protein, Asn49-Ser162. |
|
Molecular Weight |
Approximately 12.9 kDa. |
|
AA Sequence |
NWVNVISDLK KIEDLIQSMH IDATLYTESD VHPSCKVTAM KCFLLELQVI SLESGDASIH DTVENLIILA NNSLSSNGNV TESGCKECEE LEEKNIKEFL QSFVHIVQMF INTS |
|
Tag |
None |
|
Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
|
Purity |
> 97% by SDS-PAGE and HPLC analyses. |
|
Biological Activity |
The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.5 ng/mL, corresponding to a specific activity of > 2.0 × 106 IU/mg. Fully biologically active when compared to standard. |
|
Endotoxin |
< 1.0 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
|
Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -20 ℃ for 1 year.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
3 months, -20 °C under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1.Avoid repeated freeze-thaw cycles.
2.For your safety and health, please wear lab coats and disposable gloves for operation.
3.For research use only!
HB221018